Stem Cell Clinical Research: The Biology Determines the Ethics
In this response to the article by Lysaght and Campbell the author examines how many of the biological properties, such as proliferation, differentiation, and paracrine activity, that make stem cells potentially useful in clinical applications also make them potentially risky in ways that are fundamentally different from small-molecule drugs. The use of live stem cells or their derivatives in the context of cell replacement therapies thus raises issues in both the ethical treatment of human research subjects and the management of patients who may receive biologically active stem cell products.
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