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The Future of BioethicsInternational Dialogues$
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Akira Akabayashi

Print publication date: 2014

Print ISBN-13: 9780199682676

Published to Oxford Scholarship Online: January 2014

DOI: 10.1093/acprof:oso/9780199682676.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 24 October 2021

Commentary

Commentary

Stem Cell Clinical Research: The Biology Determines the Ethics

Chapter:
(p.27) 1.2 Commentary
Source:
The Future of Bioethics
Author(s):

Douglas Sipp

Publisher:
Oxford University Press
DOI:10.1093/acprof:oso/9780199682676.003.0002

In this response to the article by Lysaght and Campbell the author examines how many of the biological properties, such as proliferation, differentiation, and paracrine activity, that make stem cells potentially useful in clinical applications also make them potentially risky in ways that are fundamentally different from small-molecule drugs. The use of live stem cells or their derivatives in the context of cell replacement therapies thus raises issues in both the ethical treatment of human research subjects and the management of patients who may receive biologically active stem cell products.

Keywords:   stem cells, medical ethics, safety, efficacy

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