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Immune Responses in the Nervous System$
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Nancy J. Rothwell

Print publication date: 1997

Print ISBN-13: 9781872748795

Published to Oxford Scholarship Online: March 2012

DOI: 10.1093/acprof:oso/9781872748795.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 28 November 2020

Transplantation of neuronal and nonneuronal cells into the brain

Transplantation of neuronal and nonneuronal cells into the brain

(p.189) Chapter 9 Transplantation of neuronal and nonneuronal cells into the brain
Immune Responses in the Nervous System

H. Widner

Oxford University Press

Transplantation into the central nervous system has the potential to develop into a very powerful therapeutic approach for a variety of neurological disorders. This chapter discusses the principles of transplantation, the brain as transplantation site, transplantation of neural cells, potential therapies with intracerebral grafts, transplantation of nonneural cells, human trials with neural tissue transplants, immunological risks of transplantation, the use of immunosuppression, transplantation of transfected cells, and direct injection of oligonucleotides, virus vectors, and other noncellular approaches for gene transfer.

Keywords:   central nervous system, neural cells, intracerebral grafts, neural tissue transplants, immunosuppression, transfected cells, oligonucleotides, virus vectors

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