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Codon EvolutionMechanisms and Models$
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Gina M. Cannarozzi and Adrian Schneider

Print publication date: 2012

Print ISBN-13: 9780199601165

Published to Oxford Scholarship Online: May 2015

DOI: 10.1093/acprof:osobl/9780199601165.001.0001

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Simulation of coding sequence evolution

Simulation of coding sequence evolution

(p.126) Chapter 9 Simulation of coding sequence evolution
Codon Evolution

Miguel Arenas

David Posada

Oxford University Press

In molecular evolution, computer simulations have been commonly used to understand the interactions among evolutionary processes, for hypothesis testing, to evaluate and compare different analytical methods, or to estimate evolutionary parameters. This chapter describes simulation algorithms for the evolution of coding sequences under different evolutionary scenarios, potential uses of these simulations, and current simulation software. In particular, it discusses forward-time simulations, simulation of coalescent histories, and simulation of codon substitutions.

Keywords:   computer simulation, coding sequence, evolution, simulation algorithms

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