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Cancer Epidemiology and Prevention$
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Michael Thun, Martha S. Linet, James R. Cerhan, Christopher A. Haiman, and David Schottenfeld

Print publication date: 2017

Print ISBN-13: 9780190238667

Published to Oxford Scholarship Online: December 2017

DOI: 10.1093/oso/9780190238667.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 17 October 2021

Cancer of the Larynx

Cancer of the Larynx

(p.505) 27 Cancer of the Larynx
Cancer Epidemiology and Prevention

Andrew F. Olshan

Mia Hashibe

Oxford University Press

Cancer of the larynx can affect the glottis, supraglottis, subglottis, and laryngeal cartilage. Traditional treatments for laryngeal cancer caused significant disfigurement, difficulty with swallowing and speech, and poor quality of life. Newer treatment methods seek to preserve laryngeal function. Worldwide, an estimated 157,000 new cases and 83,000 deaths from laryngeal cancer occurred in 2012, accounting for 1.1% of all new cancer cases and 1.0% of all cancer deaths. The risk of cancer of the larynx is nearly five times higher in men than women in the United States. Incidence and mortality rates of these cancers in males are decreasing in most high-income countries; this decrease is seen in all racial and ethnic groups in the United States. Active cigarette smoking is the strongest risk factor and explains the greatest proportion of cases. All tobacco products are strongly associated with increased risk, especially when combined with alcohol consumption.

Keywords:   larynx, cancer, laryngeal cancer, smoking, alcohol

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