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Occupational and Environmental Health$
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Barry S. Levy, David H. Wegman, Sherry L. Baron, and Rosemary K. Sokas

Print publication date: 2017

Print ISBN-13: 9780190662677

Published to Oxford Scholarship Online: November 2017

DOI: 10.1093/oso/9780190662677.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2020. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 26 November 2020

Liver Disorders

Liver Disorders

(p.587) 27 Liver Disorders
Occupational and Environmental Health

Barry S. Levy

Oxford University Press

This chapter describes occupational and environmental liver disorders. It describes the types of liver function and types of liver damage, and how these functions and this damage can be assessed. Workers in healthcare and solid waste management are at increased risk hepatitis B virus and hepatitis C virus infections. Occupational exposure to swine is associated with hepatitis E virus infection. More than 100 industrial chemicals can be acutely hepatotoxic in experimental animals or humans. Metabolic reactions may affect the hepatotoxicity of chemicals. Occupational exposure to organic solvents can cause toxic hepatitis. Occupational exposure to vinyl chloride monomer has been causally associated with toxicant-associated fatty liver disease as well as a form of non-cirrhotic portal hypertension. Several agents can cause cancer of the liver or bile ducts. Vinyl chloride monomer is causally associated with angiosacoma of the liver. Arsenic causes liver cancer. Dietary exposure to aflatoxins can cause hepatoceulluar carcinoma.

Keywords:   liver disorders, hepatitis B, hepatitis C, toxic hepatitis, liver cancer, vinyl chloride monomer, arsenic, aflatoxins

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