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Epidemiology by DesignA Causal Approach to the Health Sciences$
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Daniel Westreich

Print publication date: 2019

Print ISBN-13: 9780190665760

Published to Oxford Scholarship Online: December 2019

DOI: 10.1093/oso/9780190665760.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 20 October 2021

Observational Cohort Studies

Observational Cohort Studies

(p.139) 6 Observational Cohort Studies
Epidemiology by Design

Daniel Westreich

Oxford University Press

In contrast to a randomized trial, an observational cohort study is one in which the investigator observes a group of participants with varying levels of an exposure and then follows-up those participants for a period of time to examine the incidence of one or more specified outcomes. This chapter addresses observational cohort studies in much the same way as the previous chapter addressed randomized trials: discussed are the types of cohort studies, the steps in conducting such a study, and the ways in which such studies meet or do not meet causal identification conditions. Also presented is a brief introduction to analysis. The author expands his discussion of interaction and effect measure modification, as well as generalizability, in this setting.

Keywords:   observational cohort studies, confounding, causal directed acyclic graphs, selection bias, missing data, Mantel-Haenzsel

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