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Epidemiology by DesignA Causal Approach to the Health Sciences$
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Daniel Westreich

Print publication date: 2019

Print ISBN-13: 9780190665760

Published to Oxford Scholarship Online: December 2019

DOI: 10.1093/oso/9780190665760.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2022. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use.date: 29 January 2022

Case-Control Studies

Case-Control Studies

(p.169) 7 Case-Control Studies
Epidemiology by Design

Daniel Westreich

Oxford University Press

In contrast to an observational cohort study in which participants are identified, exposures are measured, and then outcomes status is measured after follow-up, a case-control study is an observational study in which researchers sample participants based on their outcome status, often only after all outcomes have already occurred. This chapter echoes the structure of the previous two chapters in the discussion of case-control studies. In this chapter, the author’s focus is on understanding the relationship between cohort studies and case-control studies and on how the interpretation of the odds ratio estimated from the case-control study depends on the relationship of the case-control study to a cohort study.

Keywords:   case-control study, sampling, cases, controls, odds ratio, cumulative sampling, case-cohort sampling, risk-set sampling, incidence density sampling

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