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The Science of Marijuana$
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Leslie Iversen

Print publication date: 2019

Print ISBN-13: 9780190846848

Published to Oxford Scholarship Online: November 2018

DOI: 10.1093/oso/9780190846848.001.0001

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Medical Uses of Marijuana—Fact or Fantasy?

Medical Uses of Marijuana—Fact or Fantasy?

(p.113) Chapter 5 Medical Uses of Marijuana—Fact or Fantasy?
The Science of Marijuana

Leslie Iversen

Oxford University Press

Marijuana has a long history of medical use. This chapter discusses the modern revival of interest in marijuana in the United States, Europe, and elsewhere. The fully licensed cannabinoid medicines dronabinol (Marinol), nabilone (Cesamet), and nabiximols (Sativex) and their uses are discusses. Medical indications include multiple sclerosis, pain, nausea and vomiting, epilepsy, appetite stimulation, mood, sleep, and migraine. Apart from the treatment of spasticity and pain in multiple sclerosis, there is little or no scientific evidence of efficacy because of the lack of controlled clinical trials; nevertheless, there may be a significant placebo effect. The supply of cannabis to medical pharmacies is poorly controlled. The Dutch and Canadian models provide good quality control, but in the United States supplies are of patchy quality from state to state.

Keywords:   dronabinol, nabilone, nabiximols, medical indications, multiple sclerosis, rimonabant, quality control

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