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Public Mental Health$
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William W. Eaton and M. Daniele Fallin

Print publication date: 2019

Print ISBN-13: 9780190916602

Published to Oxford Scholarship Online: June 2019

DOI: 10.1093/oso/9780190916602.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 14 June 2021

Public Mental Health and the Brain Across the Life Span

Public Mental Health and the Brain Across the Life Span

(p.257) 10 Public Mental Health and the Brain Across the Life Span
Public Mental Health

Michelle C. Carlson

Kyle Moored

George W. Rebok

William W. Eaton

Oxford University Press

This chapter introduces the reader to brain structures that are hypothesized to be associated with mental and behavioral disorders. The focus is on the prefrontal-limbic and prefrontal-parietal-striatal networks as regulators of cognitive and emotional responses to internal and external stressors. These networks are increasingly understood as being plastic over the entire life course. The development of these systems from early childhood to old age is discussed, with focus on attention deficit hyperactivity disorder, schizophrenia, mood disorders, and Alzheimer’s disease. Neuroimaging tools and blood biomarkers that may help understand and prevent these disorders, as well as predict responses to therapies, are becoming increasingly useful.

Keywords:   prefrontal cortex, fronto-limbic network, default mode network, hypothalamic adrenocortical axis, oxytocin

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