Jump to ContentJump to Main Navigation
Ecology and Evolution of Infectious Diseasespathogen control and public health management in low-income countries$
Users without a subscription are not able to see the full content.

Benjamin Roche, Hélène Broutin, and Frédéric Simard

Print publication date: 2018

Print ISBN-13: 9780198789833

Published to Oxford Scholarship Online: August 2018

DOI: 10.1093/oso/9780198789833.001.0001

Show Summary Details
Page of

PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 26 January 2021

Spatial-temporal transmission dynamics and control of infectious diseases: Ebola virus disease (EVD) as a case study

Spatial-temporal transmission dynamics and control of infectious diseases: Ebola virus disease (EVD) as a case study

Chapter:
(p.43) Chapter 4 Spatial-temporal transmission dynamics and control of infectious diseases: Ebola virus disease (EVD) as a case study
Source:
Ecology and Evolution of Infectious Diseases
Author(s):

Cécile Viboud

Hélène Broutin

Gerardo Chowell

Publisher:
Oxford University Press
DOI:10.1093/oso/9780198789833.003.0004

Disentangling the spatial-temporal dynamics of infectious disease transmission is important to address issues of disease persistence, epidemic growth and optimal control. In this chapter, we review key concepts relating to the spatial-temporal dynamics of infectious diseases in meta-populations, whereby geographically separate subpopulations are connected by migration or mobility rates. We review the dynamics of colonization, persistence and extinction of emerging and recurrent pathogens in meta-populations; the role of demographic and environmental factors; and geographic heterogeneity in epidemic growth rate. We illustrate theoretical concepts by reviewing the spatial dynamics of childhood diseases and other acute infections in low- and middle-income countries, and provide a detailed description of the spatial-temporal dynamics of the 2014–16 Ebola epidemic in West Africa. We further discuss how increased availability of empirical data and recent methodological developments provide a deeper mechanistic understanding of transmission processes in space and time, and make recommendations for future work.

Keywords:   Spatial-temporal dynamics, population mobility, metapopulation, Ebola, gravity model, disease persistence, source-sink model, critical community size, epidemic growth scaling, reproduction number

Oxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us .