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Evolution and Selection of Quantitative Traits$
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Bruce Walsh and Michael Lynch

Print publication date: 2018

Print ISBN-13: 9780198830870

Published to Oxford Scholarship Online: September 2018

DOI: 10.1093/oso/9780198830870.001.0001

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Neutral Evolution in One- and Two-Locus Systems

Neutral Evolution in One- and Two-Locus Systems

(p.25) 2 Neutral Evolution in One- and Two-Locus Systems
Evolution and Selection of Quantitative Traits

Bruce Walsh

Michael Lynch

Oxford University Press

This chapter reviews the population-genetic theory of neutral alleles in finite populations, examining the probabilities and times to loss or fixation, summary statistics for molecular variation, coalescent theory (the distribution of times back to common ancestry for a sample of alleles), and both mutation-drift and mutation-drift-migration equilibrium models.

Keywords:   allele-frequency spectrum, coalescent theory, Fst, genetic drift, infinite-alleles model, infinite-sites model, island models, linkage disequilibrium, neutral theory, population structure, site-frequency spectrum, Wright-Fisher model

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