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ADHD: The Facts$
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Mark Selikowitz

Print publication date: 2021

Print ISBN-13: 9780198867371

Published to Oxford Scholarship Online: September 2021

DOI: 10.1093/oso/9780198867371.001.0001

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PRINTED FROM OXFORD SCHOLARSHIP ONLINE (oxford.universitypressscholarship.com). (c) Copyright Oxford University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in OSO for personal use. date: 18 January 2022

An impairment in brain function

An impairment in brain function

(p.89) 10 An impairment in brain function
ADHD: The Facts

Mark Selikowitz

Oxford University Press

ADHD is usually due to a depletion of certain chemical messengers in the front part of the brain. The major cause of this depletion relates to a number of defective genes. ADHD shares some of its causative genes with certain other conditions, so having ADHD makes also having these other conditions more likely. To help many children with learning and behavioural difficulties, we need to treat an impairment in their brain function. This chapter discusses impairment in brain function as a cause of ADHD, including executive function deficits, frontal lobe underactivity, neurotransmitter depletion, gene defects, and non-genetic factors. It also describes the mechanism of comorbidity.

Keywords:   ADHD, comorbidity, executive function, frontal lobe, neurotransmitter, dopamine, norepinephrine, dopamine transporter, synapse, gene defects

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